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PMID: 6684693 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The use of linked DNA polymorphisms for genotype prediction in families with Duchenne muscular dystrophy.

Journal of medical genetics ·Vol. 20 ·No. 4 ·1983-08-00 ·Pages 252-4

Harper PS, O'Brien T, Murray JM, Davies KE, Pearson P, Williamson R

Abstract

Two DNA restriction fragment length polymorphisms show genetic linkage to the Duchenne muscular dystrophy locus on the short arm of the X chromosome. Examples are given of families in which these polymorphisms can be used in the prediction of genotype for this disorder.

MeSH Terms

DNA/genetics Female Genetic Linkage Genotype Humans Male Muscular Dystrophies/diagnosis,genetics Polymorphism, Genetic X Chromosome

Chemicals

DNA

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Harper P S

O'Brien T

Murray J M

Davies K E

Pearson P

Williamson R

References (6)

6 references, click to expand

Partial preservation of pancreatic beta-cell function in children with diabetes.
Lancet. 1981 Jul 4;2(8236):1-4 PMID: 6113394
Cloning of a representative genomic library of the human X chromosome after sorting by flow cytometry.
Nature. 1981 Oct 1;293(5831):374-6 PMID: 6456416
Linkage relationship of a cloned DNA sequence on the short arm of the X chromosome to Duchenne muscular dystrophy.
Nature. 1982 Nov 4;300(5887):69-71 PMID: 6982420
First-trimester fetal diagnosis for haemoglobinopathies: three cases.
Lancet. 1982 Dec 25;2(8313):1413-6 PMID: 6129504
Linkage analysis of two cloned DNA sequences flanking the Duchenne muscular dystrophy locus on the short arm of the human X chromosome.
Nucleic Acids Res. 1983 Apr 25;11(8):2303-12 PMID: 6304647
Detection of specific sequences among DNA fragments separated by gel electrophoresis.
J Mol Biol. 1975 Nov 5;98(3):503-17 PMID: 1195397

Article Info

Journal

Journal of medical genetics

Abbr.

J Med Genet

ISSN

0022-2593

DOI

10.1136/jmg.20.4.252

Published

1983-08-00

Pages

252-4

Language

English

Region

England

NLM ID

2985087R

PMCID

PMC1049114

Subset

External Links

PubMed source DOI: 10.1136/jmg.20.4.252 PMC Full Text View journal details

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The use of linked DNA polymorphisms for genotype prediction in families with Duchenne muscular dystrophy.

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