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题目:: Surface antigens of murine hemopoietic stem cells. VIII. Antisera define lineage antigens held in common between granulocyte-macrophage cells and between lymphoid cells.
作者:: Berridge(M V)
状态:: 发布时间1984-05-24 , 更新时间 2006-11-15
期刊:: Int J Cell Cloning
摘要:: The cell-lineage model of hemopoietic cell differentiation has been further investigated by detailed absorption analysis of the anti-stem cell activity in rabbit antisera against mouse hemopoietic cells. Of seven differentiated hematopoietic cells tested, platelets alone absorbed the anti-stem cell activity in anti-platelet serum. Thymocytes and B-lymphocytes absorbed all of the anti-stem cell activity in antithymocyte serum whereas other nonlymphocytic cells showed only partial absorbing ability. Macrophages and granulocytic cells absorbed most of the anti-stem cell activity in antimacrophage serum and antineutrophil serum whereas other cell types showed little or no absorbing capacity. Antisera against a cloned mast cell precursor line showed partial cell lineage activity whereas anti-sera against eosinophils and B-lymphocytes showed no evidence of cell lineage activity. A detailed model of cell lineage antigens on hemopoietic cells is presented.
语言:: eng
DOI:: 10.1002/stem.5530010504

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