In vitro antagonism between N-formimidoyl thienamycin and aztreonam, ticarcillin and ticarcillin/clavulanic acid.

Annales de microbiologie ·Vol. 135B ·No. 1 ·1984-00-00 ·Pages 111-5

Toma EC, Morisset R, Agbaba O, Phaneuf D

Abstract

One-hundred eighty-seven bacterial strains were tested by the two-disk-agar diffusion method for the interaction between N-formimidoyl thienamycin and aztreonam, ticarcillin and ticarcillin-clavulanic acid. An antagonism between N-formimidoyl thienamycin and the other 3 beta-lactams was noted in half of the evaluable tests, especially against Pseudomonas, Escherichia coli and Morganella.

MeSH Terms

Anti-Bacterial Agents/antagonists & inhibitors Aztreonam Bacteria/drug effects Clavulanic Acid Clavulanic Acids/antagonists & inhibitors Imipenem Microbial Sensitivity Tests Penicillins/antagonists & inhibitors Thienamycins/pharmacology Ticarcillin/antagonists & inhibitors

Chemicals

Anti-Bacterial Agents Clavulanic Acids Penicillins Thienamycins Clavulanic Acid Imipenem Ticarcillin Aztreonam

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Toma E C

Morisset R

Agbaba O

Phaneuf D

Article Info

Journal

Annales de microbiologie

Abbr.

Ann Microbiol (Paris)

ISSN

0300-5410

DOI

10.1016/s0769-2609(84)80048-4

Published

1984-00-00

Pages

111-5

Language

English

Region

France

NLM ID

0354704

Subset

External Links

PubMed source DOI: 10.1016/s0769-2609(84)80048-4

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In vitro antagonism between N-formimidoyl thienamycin and aztreonam, ticarcillin and ticarcillin/clavulanic acid.

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