Two new human myeloid cell lines derived from acute promyelocytic leukemia and chronic myelocytic leukemia.

Gan ·Vol. 74 ·No. 3 ·1983-06-00 ·Pages 319-22

Kubonishi I, Machida K, Sonobe H, Ohtsuki Y, Akagi T, Miyoshi I

Abstract

Two new human myeloid cell lines, PL-21 and KCL-22, were established from acute promyelocytic leukemia and chronic myelocytic leukemia, respectively. PL-21 was positive to peroxidase staining and differentiated into mature myeloid cells in vitro. KCL-22 had Ph1 chromosomes and differentiated into granulocytes in vivo.

MeSH Terms

Adult Cell Differentiation/drug effects Cell Line Chromosome Aberrations Dimethyl Sulfoxide/pharmacology Female Humans Leukemia, Myeloid/genetics,pathology Leukemia, Myeloid, Acute/genetics,pathology Male

Chemicals

Dimethyl Sulfoxide

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Kubonishi I

Machida K

Sonobe H

Ohtsuki Y

Akagi T

Miyoshi I

Article Info

Journal

Gan

Abbr.

Gan

ISSN

0016-450X

Published

1983-06-00

Pages

319-22

Language

English

Region

Japan

NLM ID

0151745

Subset

External Links

PubMed source

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Two new human myeloid cell lines derived from acute promyelocytic leukemia and chronic myelocytic leukemia.

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