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PMID: 6572129 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

An XX male with a single STS gene dose.

Cytogenetics and cell genetics ·Vol. 35 ·No. 1 ·1983-00-00 ·Pages 72-4

Wieacker P, Voiculescu J, Müller CR, Ropers HH

Abstract

There is substantial evidence that many XX males arise from an X/Y interchange, so that a terminal Xp segment carrying the Xg locus, but not the neighboring steroid sulfatase (STS) locus, is replaced by part of the Y chromosome. We show here that one of the two X chromosomes of an XX male with low intracellular levels of STS does not express the STS gene.

MeSH Terms

Animals Female Genes Humans Hybrid Cells/physiology Male Mice Sex Chromosome Aberrations Sex Chromosomes Steryl-Sulfatase Sulfatases/genetics X Chromosome

Chemicals

Sulfatases Steryl-Sulfatase

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Wieacker P

Voiculescu J

Müller C R

Ropers H H

Article Info

Journal

Cytogenetics and cell genetics

Abbr.

Cytogenet Cell Genet

ISSN

0301-0171

DOI

10.1159/000131841

Published

1983-00-00

Pages

72-4

Language

English

Region

Switzerland

NLM ID

0367735

Subset

External Links

PubMed source DOI: 10.1159/000131841

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An XX male with a single STS gene dose.

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