Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes.

Nature ·Vol. 311 ·No. 5985 ·1984-00-00 ·Pages 438-42

Müller R, Wagner EF

Abstract

Transfer of mouse or human c-fos proto-oncogenes into F9 teratocarcinoma stem cells results in expression of c-fos mRNA and protein. This is accompanied by the appearance of morphologically altered cells which express several specific markers characteristic of differentiated cells, suggesting that c-fos plays a role in cellular differentiation.

MeSH Terms

Animals Cell Differentiation Cytoskeleton/ultrastructure Extracellular Matrix/metabolism Gene Expression Regulation Mice Oncogenes RNA, Messenger/genetics Teratoma/genetics,pathology Transfection

Chemicals

RNA, Messenger

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Müller R

Wagner E F

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/311438a0

Published

1984-00-00

Pages

438-42

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/311438a0 View journal details

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Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes.

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