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PMID: 643601 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

The location of the globin mRNA sequence within its 16S precursor.

Nucleic acids research ·Vol. 5 ·No. 1 ·1978-01-00 ·Pages 105-15

Smith K, Rosteck P, Lingrel JB

Abstract

The coding sequence of globin mRNA has been located at or very close to the 3' end of its poly(A)-containing 16S precursor. The 16S RNA was annealed to globin cDNA and the hybrid digested with ribonuclease H. The undigested fragment did not bind to oligo(dT)-cellulose and its size was that expected for the intact 5' portion of the precursor.

MeSH Terms
Animals Base Sequence Globins/genetics Mice Nucleic Acid Hybridization Nucleic Acid Precursors/genetics,isolation & purification RNA, Messenger/genetics
Chemicals
Nucleic Acid Precursors RNA, Messenger Globins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Smith K
Rosteck P
Lingrel J B
References (28)
28 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/5.1.105
Published
1978-01-00
Pages
105-15
Language
English
Region
England
NLM ID
0411011
PMCID
PMC341964
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/5.1.105 PMC Full Text View journal details
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