In vitro effect of the slime of Pseudomonas aeruginosa on the function of human polymorphonuclear neutrophils.

Infection and immunity ·Vol. 44 ·No. 3 ·1984-06-00 ·Pages 760-2

Laharrague PF, Corberand JX, Fillola G, Gleizes BJ, Fontanilles AM, Gyrard E

Abstract

The slime of Pseudomonas aeruginosa markedly impaired the in vitro motility, endocytosis, and phagosome formation of normal human polymorphonuclear neutrophils. This profound impairment of neutrophils, although without alteration of their viability, may contribute to the virulence of this microorganism.

MeSH Terms

Chemotaxis, Leukocyte Endocytosis Humans Microscopy, Electron Neutrophils/microbiology Phagocytosis Pseudomonas aeruginosa/pathogenicity

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Laharrague P F

Corberand J X

Fillola G

Gleizes B J

Fontanilles A M

Gyrard E

References (20)

20 references, click to expand

Slime of Pseudomonas aeruginosa: in vivo production.
Infect Immun. 1974 Jul;10(1):152-6 PMID: 4210337
Inhibitory effect of Pseudomonas aeruginosa on the phagocytic and killing activity of rabbit polymorphonuclear leukocytes: mechanisms of action of a polymorphonuclear leukocyte inhibitor.
Infect Immun. 1979 May;24(2):399-403 PMID: 110701
Interaction of pseudomonas exoproducts with phagocytic cells.
Can J Microbiol. 1982 Jun;28(6):679-85 PMID: 6811122
The slime of Pseudomonas aeruginosa: biological characterization and possible role in experimental infection.
J Infect Dis. 1974 Feb;129(2):101-9 PMID: 4204237
[Function of polynuclear neutrophils in the burn patient. Development during hospitalization].
Ann Chir Plast. 1979;24(3):273-8 PMID: 396871
Phagocytosis and killing of Pseudomonas aeruginosa by mouse polymorphonuclear leukocytes in vitro promoted by antiserum to the slime glycolipoprotein.
Infect Immun. 1982 Jul;37(1):378-81 PMID: 6809634
The acceleration and inhibition of migration of human leucocytes in vitro by plasma protein fractions.
J Exp Med. 1955 Jun 1;101(6):647-63 PMID: 14367686
Pseudomonas aeruginosa bacteremia in patients with neoplastic disease.
Cancer. 1972 Sep;30(3):764-73 PMID: 4627601
Letter: N.B.T. test in overwhelming bacterial infection.
Lancet. 1974 Aug 24;2(7878):465-6 PMID: 4136950
Phagocyte strategy vs. microbial tactics.
Rev Infect Dis. 1980 Sep-Oct;2(5):817-38 PMID: 7052569
Studies on the phagocytic activity of neutrophilic leukocytes.
Scand J Haematol Suppl. 1967;2:1-126 PMID: 5243720
Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leukocytes and monocytes.
J Immunol. 1975 Dec;115(6):1650-6 PMID: 1102606
Antiphagocytic Effect of Slime from a Mucoid Strain of Pseudomonas aeruginosa.
Infect Immun. 1971 Jun;3(6):762-7 PMID: 16558051
Glycolipoprotein from Pseudomonas aeruginosa as a protective antigen against P. aeruginosa infection in mice.
Infect Immun. 1977 Nov;18(2):304-9 PMID: 411754
Polymorphonuclear functions and aging in humans.
J Am Geriatr Soc. 1981 Sep;29(9):391-7 PMID: 7264130
Effects of a glycopolypeptide from the slime of P. aeruginosa on phagocytosis by mouse macrophages.
Zentralbl Bakteriol Mikrobiol Hyg A. 1983 Jul;254(4):489-99 PMID: 6426197
Quantitative nitroblue tetrazolium test in chronic granulomatous disease.
N Engl J Med. 1968 May 2;278(18):971-6 PMID: 4384563
Inhibition of granulocyte adherence by ethanol, prednisone, and aspirin, measured with an assay system.
N Engl J Med. 1974 Sep 26;291(13):642-6 PMID: 4852473
Slime production by Pseudomonas aeruginosa. II. A new synthetic medium and cultural conditions suitable for slime production by Pseudomonas aeruginosa.
Jpn J Microbiol. 1973 Jan;17(1):45-51 PMID: 4633545
Burn wounds: microbiology, local host defenses, and current therapy.
CRC Crit Rev Clin Lab Sci. 1973 Jul;4(1):61-100 PMID: 4614939

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.44.3.760-762.1984

Published

1984-06-00

Pages

760-2

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC263697

Subset

External Links

PubMed source DOI: 10.1128/iai.44.3.760-762.1984 PMC Full Text View journal details

Analysis Services

In vitro effect of the slime of Pseudomonas aeruginosa on the function of human polymorphonuclear neutrophils.

Contact

WeChat Official Account