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PMID: 6427006 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

The rate constant for ATP hydrolysis by polymerized actin.

FEBS letters ·Vol. 170 ·No. 1 ·1984-05-07 ·Pages 94-8

Pollard TD, Weeds AG

Abstract

Polymerized actin hydrolyzes bound ATP in a reaction that depends on the concentration of polymerized ATP-actin, not on the rate of incorporation of ATP-actin into the polymer. The apparent first order rate constant is about 0.07 s-1 at 21 degrees C in 50 mM KCl with 1 mM MgCl2 or CaCl2.

MeSH Terms
Actins/metabolism Adenosine Triphosphate/metabolism Animals Buffers Calcium Chloride Egtazic Acid Hydrolysis Magnesium Magnesium Chloride Mathematics Polymers/metabolism Potassium Chloride Rabbits Time Factors
Chemicals
Actins Buffers Polymers Magnesium Chloride Egtazic Acid Potassium Chloride Adenosine Triphosphate Magnesium Calcium Chloride
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Pollard T D
Weeds A G
Article Info
Journal
FEBS letters
Abbr.
FEBS Lett
ISSN
0014-5793
Published
1984-05-07
Pages
94-8
Language
English
Region
England
NLM ID
0155157
Subset
IM
Grants
NIGMS NIH HHS · GM-26132 · United States
NIGMS NIH HHS · GM-26338 · United States
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