Initial reactions involved in the dissimilation of mandelate by Rhodotorula graminis.
Rhodotorula graminis utilized DL-mandelate, L(+)-mandelate, and D(-)-mandelate as sole sources of carbon and energy. Growth on these aromatic substrates resulted in the induction of an NAD-dependent D(-)-mandelate dehydrogenase and a dye-linked L(+)-mandelate dehydrogenase, each catalyzing the stereospecific conversion of its respective enantiomer of mandelate to benzoylformate. Benzoylformate was oxidized to benzaldehyde, which was dehydrogenated to benzoate by an NAD-dependent benzaldehyde dehydrogenase. Benzoate was further metabolized through p-hydroxybenzoate and the protocatechuate branch of the beta-ketoadipate pathway.
14 references, click to expand
-
Synthesis of the enzymes of the mandelate pathway by Pseudomonas putida. I. Synthesis of enzymes by the wild type.J Bacteriol. 1966 Mar;91(3):1140-54 PMID: 5929747
-
Synthesis of the enzymes of the mandelate pathway by Pseudomonas putida. II. Isolation and properties of blocked mutants.J Bacteriol. 1966 Mar;91(3):1155-60 PMID: 5929748
-
Metabolism of mandelate and related compounds by bacterium NCIB 8250.J Gen Microbiol. 1968 Sep;53(2):259-73 PMID: 5721811
-
Involvement of the protocatechuate pathway in the metabolism of mandelic acid by Aspergillus niger.J Bacteriol. 1970 Mar;101(3):786-93 PMID: 4392397
-
Mandelic acid racemase from Pseudomonas putida. Purification and properties of the enzyme.Biochemistry. 1970 Oct 13;9(21):4029-36 PMID: 4989844
-
Mandelate racemase from Pseudomonas putida. Subunit composition and absolute divalent metal ion requirement.Biochemistry. 1974 Jun 4;13(12):2528-32 PMID: 4831901
-
Purification and characterization of a heme-containing amine dehydrogenase from Pseudomonas putida.J Bacteriol. 1978 Jun;134(3):837-43 PMID: 26667
-
Intergeneric evolutionary homology revealed by the study of protocatechuate 3,4-dioxygenase from Azotobacter vinelandii.Biochemistry. 1980 Jan 8;19(1):149-55 PMID: 6766312
-
Carbon-13 nuclear magnetic resonance studies of mandelate metabolism in whole bacterial cells and in isolated, in vivo cross-linked enzyme complexes.Biochemistry. 1981 Mar 17;20(6):1525-33 PMID: 6112014
-
Fractionation and characterization of the phosphoenolpyruvate: fructose 1-phosphotransferase system from Pseudomonas aeruginosa.J Bacteriol. 1982 Feb;149(2):534-41 PMID: 6799490
-
Dissimilation of aromatic compounds in Rhodotorula graminis: biochemical characterization of pleiotropically negative mutants.J Bacteriol. 1984 Nov;160(2):771-7 PMID: 6542098
-
Protein measurement with the Folin phenol reagent.J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
-
The enzymatic conversion of mandelic acid to benzoic acid. II. Properties of the particulate fractions.J Bacteriol. 1953 Nov;66(5):543-7 PMID: 13108853
-
The enzymatic conversion of mandelic acid to benzoic acid. III. Fractionation and properties of the soluble enzymes.J Bacteriol. 1953 Nov;66(5):548-53 PMID: 13108854
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: product@genelibs.com
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
