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PMID: 6373730 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Bacterial plasmids that carry two functional centromere analogs are stable and are partitioned faithfully.

Journal of bacteriology ·Vol. 158 ·No. 2 ·1984-05-00 ·Pages 742-5

Austin SJ

Abstract

The par genes of unit-copy plasmids P1 and F promote equitable distribution of plasmid copies to daughter cells and can be considered to be functional analogs of eucaryotic centromeres. Composite plasmids were constructed which carry either two functional P1 par regions or one F and one P1 region. Unlike dicentric chromosomes, such plasmids are stably maintained.

MeSH Terms

Centromere Chromosomes Chromosomes, Bacterial Cloning, Molecular Coliphages/genetics DNA Replication DNA, Bacterial/metabolism Escherichia coli/genetics F Factor Genes, Bacterial Genes, Viral Plasmids Recombination, Genetic

Chemicals

DNA, Bacterial

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Austin S J

References (15)

15 references, click to expand

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Two mini-F-encoded proteins are essential for equipartition.
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Relationship between chromosome replication and F'lac episome replication in Escherichia coli.
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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.158.2.742-745.1984

Published

1984-05-00

Pages

742-5

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC215495

Subset

Grants

NCI NIH HHS · N01-CO-23909 · United States

External Links

PubMed source DOI: 10.1128/jb.158.2.742-745.1984 PMC Full Text View journal details

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Bacterial plasmids that carry two functional centromere analogs are stable and are partitioned faithfully.

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