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PMID: 6369245 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

supG and supL in Escherichia coli code for mutant lysine tRNAs+.

Nucleic acids research ·Vol. 11 ·No. 23 ·1983-12-10 ·Pages 8283-6

Prather NE, Mims BH, Murgola EJ

Abstract

We have determined the nucleotide sequences of lysine tRNAs isolated from strains containing one or the other of two Escherichia coli ochre suppressors, supG and supL. Each strain, besides producing wild-type lysine tRNA, has a mutant lysine tRNA species that apparently can read the polypeptide chain termination codons UAA and UAG. The mutant tRNAs from supG and supL strains are identical. In each case the suppressor tRNA has an A36 for U36 nucleotide substitution. Furthermore, the hypermodified nucleoside at position 37 has been changed from t6A to ms2i6A.

MeSH Terms
Base Sequence Codon Escherichia coli/genetics Genes Genes, Bacterial Mutation RNA, Transfer, Amino Acyl/genetics
Chemicals
Codon RNA, Transfer, Amino Acyl
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Prather N E
Mims B H
Murgola E J
References (8)
8 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/11.23.8283
Published
1983-12-10
Pages
8283-6
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326581
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/11.23.8283 PMC Full Text View journal details
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