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PMID: 6366549 Published · ppublish English Journal Article Review

Kinetoplast DNA, mitochondrial DNA with a difference.

Molecular and biochemical parasitology ·Vol. 9 ·No. 2 ·1983-10-00 ·Pages 93-104

Stuart K

Abstract

Kinetoplast DNA occurs in flagellated protozoa belonging to the order Kinetoplastida. Kinetoplast DNA contains tens of maxicircles and thousands of minicircles which are catenated into a single network in each cell. Maxicircles contain genetic information analogous to that in other mitochondrial DNAs. Maxicircles encode mitochondrial ribosomal RNAs and hybridize with mitochondrial gene sequences from other organisms. Minicircles evolve rapidly, may not be transcribed, and vary greatly in total complexity among genera. The functions of minicircles and the network structure are unknown.

MeSH Terms
Animals DNA/metabolism DNA Replication DNA, Fungal/metabolism Eukaryota/genetics,metabolism Leishmania/metabolism Mitochondria/metabolism Plants/genetics RNA, Transfer/metabolism Ribosomes/metabolism Species Specificity Transcription, Genetic Trypanosoma/metabolism
Chemicals
DNA, Fungal DNA RNA, Transfer
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Stuart K
Article Info
Journal
Molecular and biochemical parasitology
Abbr.
Mol Biochem Parasitol
ISSN
0166-6851
Published
1983-10-00
Pages
93-104
Language
English
Region
Netherlands
NLM ID
8006324
Subset
IM
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