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PMID: 6355036 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Osteoclasts and monocytes have similar cytoskeletal structures and adhesion property in vitro.

Journal of anatomy ·Vol. 137 (Pt 1) ·1983-08-00 ·Pages 57-70

Zallone AZ, Teti A, Primavera MV, Naldini L, Marchisio PC

Abstract

The distribution of some cytoskeletal structures (microtubules, microfilaments, intermediate filaments) has been studied by indirect immunofluorescence microscopy and affinity purified antibodies in osteoclasts isolated from medullary bone of laying hens and in hen blood monocytes cultured in vitro. Both cell types show similar patterns of distribution of cytoskeletal structures and this further supports the concept that these cells are closely related. Osteoclasts and monocytes are also similar in their adhesion patterns, because they adhere to fibronectin-free areas and show closely comparable cell-to-substrate interactions when observed with interference reflection microscopy.

MeSH Terms
Animals Cell Adhesion Cells, Cultured Chickens Female Fibronectins/analysis Microscopy, Fluorescence Microscopy, Phase-Contrast Microtubules Monocytes/analysis,cytology Osteoclasts/analysis,cytology
Chemicals
Fibronectins
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Zallone A Z
Teti A
Primavera M V
Naldini L
Marchisio P C
References (26)
26 references, click to expand
  1. The isolation and selected properties of blood monocytes.
    J Exp Med. 1966 Jan 1;123(1):145-60 PMID: 4285446
  2. Actin-like filaments in bone cells of cultured mouse calvaria as demonstrated by binding to heavy meromyosin.
    J Cell Biol. 1975 Aug;66(2):445-51 PMID: 1095601
  3. The origin and fate of osteoclasts.
    Anat Rec. 1975 Sep;183(1):1-11 PMID: 1101733
  4. Cytoplasmic microtubules in tissue culture cells appear to grow from an organizing structure towards the plasma membrane.
    Proc Natl Acad Sci U S A. 1976 Mar;73(3):867-71 PMID: 1062799
  5. Cell-to-substrate contacts in living fibroblasts: an interference reflexion study with an evaluation of the technique.
    J Cell Sci. 1976 Jun;21(1):129-59 PMID: 932106
  6. Griseofulvin interacts with microtubules both in vivo and in vitro.
    J Mol Biol. 1976 Apr 25;102(4):817-29 PMID: 781264
  7. The display of microtubules in transformed cells.
    Cell. 1977 Nov;12(3):561-71 PMID: 200367
  8. Some morphological observations on osteoclasts.
    Cell Tissue Res. 1977 Dec 19;185(3):387-97 PMID: 597853
  9. Cell to substratum contacts of chick fibroblasts and their relation to the microfilament system. A correlated interference-reflexion and high-voltage electron-microscope study.
    J Cell Sci. 1978 Feb;29:197-212 PMID: 564353
  10. Changes in intracellular organization of tubulin and actin in N-18 neuroblastoma cells during the process of axon extension induced by serum deprivation.
    Brain Res. 1978 Oct 27;155(2):229-37 PMID: 356932
  11. Serological characterization of human monocytes for HLA, B-lymphocyte, granulocyte, and monocyte-associated antigens by cytotoxicity testing.
    Tissue Antigens. 1978 May;11(5):385-93 PMID: 308716
  12. The intracellular organization of actin and tubulin in cultured C-1300 mouse neuroblastoma cells (clone NB41A3).
    J Neurocytol. 1978 Oct;7(5):571-82 PMID: 214525
  13. Different intermediate-sized filaments distinguished by immunofluorescence microscopy.
    Proc Natl Acad Sci U S A. 1978 Oct;75(10):5034-8 PMID: 368806
  14. Cell-to-substratum contacts in living cells: a direct correlation between interference-reflexion and indirect-immunofluorescence microscopy using antibodies against actin and alpha-actinin.
    J Cell Sci. 1979 Jun;37:257-73 PMID: 383732
  15. A 130K protein from chicken gizzard: its localization at the termini of microfilament bundles in cultured chicken cells.
    Cell. 1979 Sep;18(1):193-205 PMID: 574428
  16. Intermediate filaments as mechanical integrators of cellular space.
    Nature. 1980 Jan 17;283(5744):249-256 PMID: 7188712
  17. Formation of cell-to-substrate contacts during fibroblast motility: an interference-reflexion study.
    J Cell Sci. 1980 Apr;42:81-116 PMID: 7400245
  18. Cytoskeletal F-actin patterns quantitated with fluorescein isothiocyanate-phalloidin in normal and transformed cells.
    Proc Natl Acad Sci U S A. 1980 Nov;77(11):6624-8 PMID: 6256751
  19. Appearance of fibronectin during the differentiation of cartilage, bone, and bone marrow.
    J Cell Biol. 1981 Mar;88(3):630-6 PMID: 7217207
  20. Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formation.
    Proc Natl Acad Sci U S A. 1981 May;78(5):3005-9 PMID: 6789327
  21. The removal of extracellular fibronectin from areas of cell-substrate contact.
    Cell. 1981 Jul;25(1):121-32 PMID: 6791830
  22. New knowledge on the origin, function and fate of osteoclasts.
    Clin Orthop Relat Res. 1981 Jul-Aug;(158):252-69 PMID: 6268344
  23. Formation of osteoclasts from blood monocytes during 1 alpha-OH Vit D-stimulated bone resorption in mice.
    J Anat. 1981 Oct;133(Pt 3):389-96 PMID: 7328045
  24. Recruitment of osteoclast precursors by purified bone matrix constituents.
    J Cell Biol. 1982 Jan;92(1):227-30 PMID: 6976967
  25. Cell-to-substrate contacts in an adhesion-defective mutant of Balb/c3T3 cells.
    J Cell Sci. 1981 Dec;52:183-96 PMID: 7334056
  26. Motion picture and electron microscope studies on the embryonic avian osteoclast.
    J Biophys Biochem Cytol. 1961 Dec;11:651-61 PMID: 13904295
Article Info
Journal
Journal of anatomy
Abbr.
J Anat
ISSN
0021-8782
Published
1983-08-00
Pages
57-70
Language
English
Region
England
NLM ID
0137162
PMCID
PMC1171792
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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