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PMID: 6352043 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Calcium-binding protein in the developing rat cerebellum. An immunocytochemical study.

Cell and tissue research ·Vol. 233 ·No. 2 ·1983-00-00 ·Pages 389-402

Legrand C, Thomasset M, Parkes CO, Clavel MC, Rabié A

Abstract

Specific antibodies raised against a human 28 000 dalton cerebellar calcium-binding protein (CaBP) were used in an immunocytochemical study during development of the rat cerebellum. Both light and electron microscopy showed (1) that labelling was entirely restricted to the Purkinje cells, (2) that it appeared very early in Purkinje cell development, (3) that the entire cell was labelled from the tip of the smallest dendrites to the axonal terminals, and (4) that with increasing age, the immunoreaction appeared to be progressively restricted to the cell and organelle membranes.

MeSH Terms
Animals Anura Calcium-Binding Proteins/analysis Cerebellar Cortex/analysis Cerebellum/analysis,cytology,embryology Histocytochemistry Humans Immunologic Techniques Purkinje Cells/analysis Rabbits Rats Rats, Inbred Strains
Chemicals
Calcium-Binding Proteins
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Legrand C
Thomasset M
Parkes C O
Clavel M C
Rabié A
References (19)
19 references, click to expand
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Article Info
Journal
Cell and tissue research
Abbr.
Cell Tissue Res
ISSN
0302-766X
DOI
10.1007/BF00238305
Published
1983-00-00
Pages
389-402
Language
English
Region
Germany
NLM ID
0417625
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00238305 View journal details
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