Home LiteratureArticle Details
PMID: 6349397 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

In vitro cultivation of the exoerythrocytic stage of Plasmodium berghei in a hepatoma cell line.

The American journal of tropical medicine and hygiene ·Vol. 32 ·No. 4 ·1983-07-00 ·Pages 682-4

Hollingdale MR, Leland P, Schwartz AL

Abstract

When inoculated with sporozoites of Plasmodium berghei, a line of hepatoma cells (HepG2-A16) derived from human liver supports the complete asexual developmental cycle of the exoerythrocytic stage. Parasites were shown to resemble parasites in vivo in hepatocytes. Subinoculation of merozoites into mice induced a red blood cell infection.

MeSH Terms
Animals Erythrocytes/parasitology In Vitro Techniques Liver Neoplasms, Experimental/parasitology Malaria/parasitology Mice Mice, Inbred Strains Plasmodium berghei/parasitology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hollingdale M R
Leland P
Schwartz A L
Article Info
Journal
The American journal of tropical medicine and hygiene
Abbr.
Am J Trop Med Hyg
ISSN
0002-9637
DOI
10.4269/ajtmh.1983.32.682
Published
1983-07-00
Pages
682-4
Language
English
Region
United States
NLM ID
0370507
Subset
IM
External Links
PubMed source DOI: 10.4269/ajtmh.1983.32.682 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2