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PMID: 6330209 Published · ppublish English Case Reports Journal Article

Systemic infection by Rhodotorula spp. in the immunocompromised host.

The Journal of infection ·Vol. 8 ·No. 3 ·1984-05-00 ·Pages 241-6

Rusthoven JJ, Feld R, Tuffnell PG

Abstract

Invasive fungal disease continues to be a significant problem among immunocompromised patients. We report a case of systemic Rhodotorula infection in a patient with acute myelogenous leukaemia. Rhodotorula was isolated from bone marrow on two separate occasions despite initial treatment with amphotericin B. Liver computerised tomographic scan suggested liver abscesses, and yeasts were seen on biopsy. The patient survived after aggressive antifungal and antileukaemia treatment. Rhodotorula fungaemia has been occasionally associated with shock. As our case illustrates, Rhodoturola may be a cause of invasive fungal disease in the immunocompromised host but can be eradicated if treated aggressively.

MeSH Terms
Adult Amphotericin B/therapeutic use Bone Marrow/microbiology Flucytosine/therapeutic use Humans Ketoconazole/therapeutic use Leukemia, Myeloid, Acute/complications Liver Abscess/drug therapy,etiology,immunology Male Mitosporic Fungi Mycoses/complications,drug therapy,immunology Rhodotorula
Chemicals
Amphotericin B Flucytosine Ketoconazole
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Rusthoven J J
Feld R
Tuffnell P G
Article Info
Journal
The Journal of infection
Abbr.
J Infect
ISSN
0163-4453
Published
1984-05-00
Pages
241-6
Language
English
Region
England
NLM ID
7908424
Subset
IM
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