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PMID: 6325933 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Duplication within the haptoglobin Hp2 gene.

Nature ·Vol. 309 ·No. 5964 ·1984-00-00 ·Pages 131-5

Maeda N, Yang F, Barnett DR, Bowman BH, Smithies O

Abstract

DNA sequencing shows that the intragenic duplication within the human haptoglobin Hp2 allele was formed by a non-homologous, probably random, crossing-over within different introns of two Hp1 genes, probably in an Hp1F / Hp1S heterozygote.

MeSH Terms
Alleles Amino Acid Sequence Base Sequence Crossing Over, Genetic DNA Restriction Enzymes Genes Genotype Haptoglobins/genetics Heterozygote Humans
Chemicals
Haptoglobins DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Maeda N
Yang F
Barnett D R
Bowman B H
Smithies O
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/309131a0
Published
1984-00-00
Pages
131-5
Language
English
Region
England
NLM ID
0410462
Subset
IM
Grants
NIADDK NIH HHS · AM20120 · United States
NIGMS NIH HHS · GM20069 · United States
NICHD NIH HHS · HD16584 · United States
Databases
GENBANK
X00606
External Links
PubMed source DOI: 10.1038/309131a0 View journal details
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