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PMID: 6325396 Published · ppublish English Journal Article

Interaction between IIIGlc of the phosphoenolpyruvate:sugar phosphotransferase system and glycerol kinase of Salmonella typhimurium.

Journal of bacteriology ·Vol. 158 ·No. 1 ·1984-04-00 ·Pages 351-3

Postma PW, Epstein W, Schuitema AR, Nelson SO

Abstract

Purified IIIGlc of the phosphoenolpyruvate:sugar phosphotransferase system of Salmonella typhimurium inhibits glycerol kinase. Phosphorylation of IIIGlc via phosphoenolpyruvate, enzyme I, and HPr abolishes this inhibition. The glycerol facilitator is not inhibited by IIIGlc. It is proposed that regulation of glycerol metabolism by the phosphoenolpyruvate:sugar phosphotransferase system is at the level of glycerol kinase.

MeSH Terms
Bacterial Proteins/pharmacology Escherichia coli Proteins Glycerol/metabolism Glycerol Kinase/antagonists & inhibitors Phosphoenolpyruvate/pharmacology Phosphoenolpyruvate Sugar Phosphotransferase System/metabolism,pharmacology Phosphorylation Phosphotransferases/antagonists & inhibitors Phosphotransferases (Nitrogenous Group Acceptor) Salmonella typhimurium/enzymology
Chemicals
Bacterial Proteins Escherichia coli Proteins crr protein, E coli Phosphoenolpyruvate Phosphotransferases Phosphoenolpyruvate Sugar Phosphotransferase System phosphocarrier protein HPr Glycerol Kinase Phosphotransferases (Nitrogenous Group Acceptor) phosphoenolpyruvate-protein phosphotransferase Glycerol
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Postma P W
Epstein W
Schuitema A R
Nelson S O
References (17)
17 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.158.1.351-353.1984
Published
1984-04-00
Pages
351-3
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC215423
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.158.1.351-353.1984 PMC Full Text View journal details
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