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PMID: 6321349 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Killing of Aspergillus fumigatus spores and Candida albicans yeast phase by the iron-hydrogen peroxide-iodide cytotoxic system: comparison with the myeloperoxidase-hydrogen peroxide-halide system.

Infection and immunity ·Vol. 43 ·No. 3 ·1984-03-00 ·Pages 1100-2

Levitz SM, Diamond RD

Abstract

A new fungicidal system composed of ferrous ion, H2O2, and iodide is described and compared with the myeloperoxidase-hydrogen peroxide-halide system. Both systems had similar activity against Aspergillus fumigatus spores and the Candida albicans yeast phase, but only the ferrous ion-hydrogen peroxide-iodide system was inhibited by hydroxyl radical scavengers.

MeSH Terms
Animals Antifungal Agents/pharmacology Aspergillus fumigatus/drug effects,physiology Candida albicans/drug effects,physiology Dogs Ferrous Compounds/pharmacology Hydrogen Peroxide/pharmacology Iodides/pharmacology Neutrophils/physiology Oxygen Consumption/drug effects Peroxidase/pharmacology Spores/drug effects
Chemicals
Antifungal Agents Ferrous Compounds Iodides Hydrogen Peroxide Peroxidase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Levitz S M
Diamond R D
References (20)
20 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.43.3.1100-1102.1984
Published
1984-03-00
Pages
1100-2
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC264303
Subset
IM
Grants
NIAID NIH HHS · AI15338 · United States
External Links
PubMed source DOI: 10.1128/iai.43.3.1100-1102.1984 PMC Full Text View journal details
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