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PMID: 6311167 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The fatty acid composition of 1,2-diacylglycerol and polyphosphoinositides from human erythrocyte membranes.

The Biochemical journal ·Vol. 213 ·No. 2 ·1983-08-01 ·Pages 555-7

Allan D, Cockcroft S

Abstract

The fatty acid compositions of 1,2-diacylglycerol and polyphosphoinositides have been determined in human erythrocyte membranes that have been incubated in the presence or in the absence of Ca2+. The results show that the diacylglycerol that is formed in Ca2+-treated membranes has a fatty acid composition closely similar to that of the inositides, consistent with previous indications that Ca2+ stimulates the activity of a polyphosphoinositide phosphodiesterase in the membranes. In contrast with some previous results, it appears that these plasma-membrane inositides and their derived diacylglycerols are rich in stearic acid and arachidonic acid.

MeSH Terms

Calcium/pharmacology Diglycerides/blood Erythrocyte Membrane/analysis,drug effects Erythrocytes/analysis Fatty Acids/blood Glycerides/blood Humans Phosphatidylinositol Phosphates Phosphatidylinositols/blood

Chemicals

1,2-diacylglycerol Diglycerides Fatty Acids Glycerides Phosphatidylinositol Phosphates Phosphatidylinositols Calcium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Allan D

Cockcroft S

References (14)

14 references, click to expand

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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj2130555

Published

1983-08-01

Pages

555-7

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1152163

Subset

External Links

PubMed source DOI: 10.1042/bj2130555 PMC Full Text View journal details

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The fatty acid composition of 1,2-diacylglycerol and polyphosphoinositides from human erythrocyte membranes.

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