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题目:: Mononuclear cells in malignant and benign human breast tissue.
作者:: Giorno(R)
状态:: 发布时间1983-08-26 , 更新时间 2005-11-17
期刊:: Arch Pathol Lab Med
摘要:: The mononuclear cell infiltrate in benign and malignant breast tissue was studied using monoclonal antibodies with an immunoenzymatic technique. Infiltrating duct carcinomas contained a mononuclear cell infiltrate made up mostly of T lymphocytes, with minor B-cell and macrophage populations. The most preponderant T-cell subset was the T8, cytotoxic-suppressor cell. Some tumors contained T6-positive cells, possibly immature T cells. In contrast, stromal lymphocytes in benign fibrous mastopathy were largely T cells, but the T4, helper-inducer cell was the most preponderant, and T6 cells were not detected. Intraepithelial lymphocytes were identified in benign breast tissue. Intraepithelial lymphocytes are T cells, with a great preponderance of the T8 phenotype. The T6-positive cells were also identified within the epithelium, but they seemed to represent myoepithelial cells rather than immature T cells.
语言:: eng
DOI:

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