Primary hepatic tumors of childhood.

Human pathology ·Vol. 14 ·No. 6 ·1983-06-00 ·Pages 512-37

Weinberg AG, Finegold MJ

Abstract

A clinicopathologic review of 73 cases of primary liver tumors at Texas Children's Hospital, Houston, and Children's Medical Center, Dallas, has documented important prognostic and therapeutic implications for the histologic classification of hepatoblastoma. The pure "fetal" pattern was associated with cure in every instance that surgical excision was achieved (six of six patients), whereas only two of 19 patients with "embryonal" or other undifferentiated patterns of growth survived five years. The relationship of hepatoblastoma and hepatocarcinoma in childhood to antecedent conditions is discussed in detail. The uncommon liver sarcomas are also reviewed in the light of experience at these two institutions.

MeSH Terms

Adenocarcinoma/pathology Adenoma/pathology Adolescent Adult Bile Duct Neoplasms/pathology Bile Ducts/abnormalities Carcinoma, Hepatocellular/classification,complications,pathology Child Child, Preschool Female Hemangioma/pathology Hemangiosarcoma/pathology Hepatitis/complications Hepatitis B/complications Humans Hyperplasia/pathology Infant Liver Cirrhosis, Biliary/complications Liver Neoplasms/classification,complications,pathology Male Metabolism, Inborn Errors/complications,genetics Neoplasms, Germ Cell and Embryonal/pathology Prognosis Sex Factors Tyrosine/blood

Chemicals

Tyrosine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Weinberg A G

Finegold M J

Article Info

Journal

Human pathology

Abbr.

Hum Pathol

ISSN

0046-8177

DOI

10.1016/s0046-8177(83)80005-7

Published

1983-06-00

Pages

512-37

Language

English

Region

United States

NLM ID

9421547

Subset

External Links

PubMed source DOI: 10.1016/s0046-8177(83)80005-7 View journal details

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Primary hepatic tumors of childhood.

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