Oncogene from human EJ bladder carcinoma is located on the short arm of chromosome 11.

Science (New York, N.Y.) ·Vol. 219 ·No. 4584 ·1983-02-04 ·Pages 498-501

de Martinville B, Giacalone J, Shih C, Weinberg RA, Francke U

Abstract

The human cellular homolog of the transforming DNA sequence isolated from the bladder carcinoma cell line EJ was localized on the short arm of human chromosome 11 by Southern blot analysis of human-rodent hybrid cell DNA. This locus contains human sequences homologous to the Harvey murine sarcoma virus v-Ha-ras oncogene.

MeSH Terms

Cell Line Chromosome Mapping Chromosomes, Human, 6-12 and X DNA Restriction Enzymes Humans Hybrid Cells Nucleic Acid Hybridization Oncogenes Urinary Bladder Neoplasms/genetics

Chemicals

DNA Restriction Enzymes

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

de Martinville B

Giacalone J

Shih C

Weinberg R A

Francke U

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.6297001

Published

1983-02-04

Pages

498-501

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.6297001 View journal details

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Oncogene from human EJ bladder carcinoma is located on the short arm of chromosome 11.

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