Serum copper and related variables in rheumatoid arthritis.

Annals of the rheumatic diseases ·Vol. 37 ·No. 1 ·1978-02-00 ·Pages 67-70

Scudder PR, Al-Timimi D, McMurray W, White AG, Zoob BC, Dormandy TL

Abstract

Serum copper, caeruloplasmin, iron, iron-binding capacity, and antioxidant activity were measured in 120 normal subjects and in 189 patients with rheumatoid arthritis. Both serum copper and serum caeruloplasmin were significantly raised in rheumatoid disease in both sexes. A significant inverse relation was found between serum iron and serum copper, and a strong direct correlation between serum antioxidant activity and caeruloplasmin.

MeSH Terms

Adult Aged Antioxidants/metabolism Arthritis, Rheumatoid/blood Ceruloplasmin/metabolism Copper/blood Female Humans Iron/blood Male Middle Aged Sex Factors

Chemicals

Antioxidants Copper Iron Ceruloplasmin

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Scudder P R

Al-Timimi D

McMurray W

White A G

Zoob B C

Dormandy T L

References (13)

13 references, click to expand

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Significance of plasma copper and caeruloplasmin concentrations in rheumatoid arthritis.
Ann Rheum Dis. 1975 Apr;34(2):162-5 PMID: 49178
Determination of gold in body fluids by atomic absorption spectrophotometry.
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Immunochemistry. 1965 Sep;2(3):235-54 PMID: 4956917
Serum ceruloplasmin concentration in rheumatoid arthritis, ankylosing spondylitis, psoriasis and sarcoidosis.
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Ann Rheum Dis. 1975 Aug;34(4):340-5 PMID: 1190853
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Article Info

Journal

Annals of the rheumatic diseases

Abbr.

Ann Rheum Dis

ISSN

0003-4967

DOI

10.1136/ard.37.1.67

Published

1978-02-00

Pages

67-70

Language

English

Region

England

NLM ID

0372355

PMCID

PMC1000192

Subset

External Links

PubMed source DOI: 10.1136/ard.37.1.67 PMC Full Text View journal details

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