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PMID: 6294585 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Isolated bovine ventricular myocytes. Characterization of the action potential.

Pflugers Archiv : European journal of physiology ·Vol. 395 ·No. 1 ·1982-10-00 ·Pages 19-29

Isenberg G, Klöckner U

Abstract

暂无摘要

MeSH Terms
Action Potentials/drug effects Animals Calcium/pharmacology,physiology Cattle Electric Stimulation Heart/physiology Heart Ventricles/cytology Ion Channels Sodium/physiology Time Factors
Chemicals
Ion Channels Sodium Calcium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Isenberg G
Klöckner U
References (69)
69 references, click to expand
  1. Influence of changes in external potassium and chloride ions on membrane potential and intracellular potassium ion activity in rabbit ventricular muscle.
    J Physiol. 1976 Apr;256(3):663-89 PMID: 1271296
  2. Effects of calcium ions and local anesthetics on electrical properties of Purkinje fibres.
    J Physiol. 1955 Sep 28;129(3):568-82 PMID: 13264118
  3. Properties of two inward membrane currents in the heart.
    Annu Rev Physiol. 1979;41:413-24 PMID: 373598
  4. The effect of the cardiac membrane potential on the rapid availability of the sodium-carrying system.
    J Physiol. 1955 Jan 28;127(1):213-24 PMID: 14354640
  5. The ultrastructure of membrane alterations of enzymatically dissociated cardiac myocytes.
    J Mol Cell Cardiol. 1979 Nov;11(11):1151-63 PMID: 230356
  6. Cardiac Purkinje fibers: cesium as a tool to block inward rectifying potassium currents.
    Pflugers Arch. 1976 Sep 30;365(2-3):99-106 PMID: 988568
  7. Slow recovery of (dV/dt)max in sheep cardiac Purkinje fibers.
    Arch Int Pharmacodyn Ther. 1980 Apr;244(2):344 PMID: 7190812
  8. Uniform sarcomere shortening behavior in isolated cardiac muscle cells.
    J Gen Physiol. 1980 Nov;76(5):587-607 PMID: 7441197
  9. Activities of potassium and sodium ions in rabbit heart muscle.
    J Gen Physiol. 1975 Jun;65(6):695-708 PMID: 1194884
  10. Cyclic AMP and contractile activity in heart.
    Adv Cyclic Nucleotide Res. 1977;8:363-420 PMID: 21550
  11. Electrical and mechanical responses from ventricular muscle fibers after inactivation of the sodium carrying system.
    Pflugers Arch. 1970;317(4):359-72 PMID: 5463659
  12. Voltage-dependent action of tetrodotoxin in mammalian cardiac muscle.
    Nature. 1976 Sep 23;263(5575):344-5 PMID: 958493
  13. Analysis of the effects of changes in rate and rhythm upon electrical activity in the heart.
    Prog Biophys Mol Biol. 1980;36(1):1-52 PMID: 7001542
  14. Slow recovery from inactivation of inward currents in mammalian myocardial fibres.
    J Physiol. 1974 Aug;240(3):703-24 PMID: 4415790
  15. Cow ventricular muscle. I. The effect of the extracellular potassium concentration on the current-voltage relationship. II. Evidence for a time-dependent outward current.
    Pflugers Arch. 1980 Dec;389(1):37-44 PMID: 7193465
  16. The voltage- and time-dependent effects of (-)-verapamil on the slow inward current in isolated cat ventricular myocardium.
    J Pharmacol Exp Ther. 1978 Oct;207(1):49-55 PMID: 702350
  17. Influence of low extracellular pH upon the Ca inward current and isometric contractile force in mammalian ventricular myocardium.
    Pflugers Arch. 1976 Oct 15;366(1):31-8 PMID: 10549
  18. [Influence of the frequency of contraction on the action potential of the guinea pig papillary muscle].
    Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;260(4):342-65 PMID: 4234605
  19. The structure and function of the myocardial cell surface.
    Am J Physiol. 1978 Nov;235(5):H461-8 PMID: 727267
  20. Ultrastructural studies of metabolically active isolated adult rat heart myocytes.
    J Mol Cell Cardiol. 1978 May;10(5):449-59 PMID: 207874
  21. The relation of Vmax to INa, GNa, and h infinity in a model of the cardiac Purkinje fiber.
    Biophys J. 1979 Mar;25(3):407-20 PMID: 262397
  22. Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium".
    Pflugers Arch. 1982 Oct;395(1):6-18 PMID: 7177773
  23. Calcium-dependent action potentials produced by catecholamines in guinea pig atrial muscle fibers depolarized by potassium.
    Circ Res. 1970 Sep;27(3):379-90 PMID: 5452736
  24. Control of action potential duration by calcium ions in cardiac Purkinje fibers.
    J Gen Physiol. 1976 May;67(5):599-617 PMID: 1271045
  25. Distribution of ions and water between tissue compartments in the perfused left ventricle of the rat heart.
    Circ Res. 1968 Mar;22(3):435-46 PMID: 5639053
  26. Adrenaline and the plateau phase of the cardiac action potential. Importance of Ca++, Na+ and K+ conductance.
    Pflugers Arch. 1969;313(4):300-15 PMID: 4391401
  27. Calcium channel.
    Annu Rev Neurosci. 1981;4:69-125 PMID: 6261668
  28. Analysis of the inhibitory effect of Ni ions on slow inward current in mammalian ventricular myocardium.
    J Mol Cell Cardiol. 1979 Dec;11(12):1227-43 PMID: 529295
  29. Calcium ion effects on the rising phases of action potentials obtained from guinea-pig papillary muscles at different potassium concentrations.
    J Mol Cell Cardiol. 1981 May;13(5):457-69 PMID: 7265255
  30. Development of sensitivity to tetrodotoxin in beating chick embryo hearts, single cells, and aggregates.
    Science. 1972 Jun 16;176(4040):1248-50 PMID: 5033643
  31. The effect of tetrodotoxin on the membrane current in cardiac muscle (Purkinje fibers).
    Pflugers Arch Gesamte Physiol Menschen Tiere. 1967;295(3):213-26 PMID: 5241427
  32. Studies on the inhibitory effect of verapamil on the slow inward current in mammalian ventricular myocardium.
    J Mol Cell Cardiol. 1978 Nov;10(11):1037-52 PMID: 722800
  33. Effects of adrenaline on membrane inward currents during the cardiac action potential.
    Pflugers Arch. 1969;309(1):70-81 PMID: 5815320
  34. The potassium component of membrane current in Purkinje fibers.
    Pflugers Arch Gesamte Physiol Menschen Tiere. 1967;296(4):308-27 PMID: 5239190
  35. Current-voltage relations in ventricular muscle preparations from different species.
    Pflugers Arch. 1978 Apr 25;374(1):79-89 PMID: 567335
  36. Glycocalyx is not required for show inward calcium current in isolated rat heart myocytes.
    Nature. 1980 Mar 27;284(5754):358-60 PMID: 6244505
  37. K efflux through inward rectifying K channels in voltage clamped Purkinje fibers.
    Pflugers Arch. 1980 Apr;384(3):207-17 PMID: 6251423
  38. Chemicals as tools in the study of excitable membranes.
    Physiol Rev. 1974 Oct;54(4):813-89 PMID: 4153804
  39. Development of sensitivity to tetrodotoxin of chick embryonic hearts with age.
    J Mol Cell Cardiol. 1971 Dec;3(3):271-86 PMID: 5293984
  40. Adult canine myocytes: isolation, morphology and biochemical characteristics.
    J Mol Cell Cardiol. 1979 Apr;11(4):339-57 PMID: 155746
  41. Cardiac Purkinje fibres: [Ca2+]i controls the potassium permeability via the conductance components gK1 and gK2.
    Pflugers Arch. 1977 Oct 19;371(1-2):77-85 PMID: 413096
  42. Trypsin inhibits the action of tetrodotoxin on neurones.
    Nature. 1977 Feb 24;265(5596):751-3 PMID: 859585
  43. Cardiac action potential and inotropic effect of noradrenaline and calcium.
    Naunyn Schmiedebergs Arch Pharmacol. 1975;286(4):337-51 PMID: 1143351
  44. [On the influence of the extracellular Ca concentration on membrane potential and contraction of isolated heart preparations during graded depolarization].
    Pflugers Arch Gesamte Physiol Menschen Tiere. 1968;300(2):87-107 PMID: 5242141
  45. Effects of K+ and K+-induced polarization on (dV/dt)max, threshold potential, and membrane input resistance in guinea pig and cat ventricular myocardium.
    Circ Res. 1979 Jun;44(6):800-14 PMID: 428073
  46. On the mechanism of slow calcium channel block in heart.
    Pflugers Arch. 1980 May;385(2):175-9 PMID: 6248838
  47. Potassium efflux in heart muscle during activity: extracellular accumulation and its implications.
    J Physiol. 1978 Jul;280:537-58 PMID: 308540
  48. Calcium and cardiac excitation-contraction coupling.
    Annu Rev Physiol. 1979;41:473-84 PMID: 373601
  49. Voltage clamp experiments on ventricular myocarial fibres.
    J Physiol. 1970 Mar;207(1):165-90 PMID: 5503866
  50. Sodium current in single rat heart muscle cells.
    J Physiol. 1981 Sep;318:479-500 PMID: 7320902
  51. Risk and advantages of using strongly beveled microelectrodes for electrophysiological studies in cardiac Purkinje fibers.
    Pflugers Arch. 1979 May 15;380(1):91-8 PMID: 572044
  52. Effect of calcium concentration on the transmembrane potentials of Purkinje fibers.
    Circ Res. 1967 Jan;20(1):32-44 PMID: 5623945
  53. Inactivation of Ca conductance dependent on entry of Ca ions in molluscan neurons.
    Proc Natl Acad Sci U S A. 1979 Mar;76(3):1497-500 PMID: 286336
  54. Voltage clamp and internal perfusion of single rat heart muscle cells.
    J Physiol. 1981 Sep;318:455-77 PMID: 7320901
  55. Electrophysiology of single cardiac cells.
    Physiol Rev. 1958 Jan;38(1):41-76 PMID: 13505115
  56. Lack of effect of neuraminidase on responses of isolated guinea-pig heart preparations to ouabain.
    J Mol Cell Cardiol. 1980 Dec;12(12):1471-4 PMID: 7205961
  57. Inotropic effects of electric currents. I. Positive and negative effects of constant electric currents or current pulses applied during cardiac action potentials. II. Hypotheses: calcium movements, excitation-contraction coupling and inotropic effects.
    Circ Res. 1969 Mar;24(3):409-45 PMID: 5766519
  58. A study of the ion selectivity and the kinetic properties of the calcium dependent slow inward current in mammalian cardiac muscle.
    J Physiol. 1977 Jan;264(1):17-47 PMID: 839451
  59. The regulation of the calcium conductance of cardiac muscle by adrenaline.
    J Physiol. 1977 Jan;264(1):49-62 PMID: 839456
  60. Removal of sialic acid from cardiac sarcolemma does not affect contractile function in electrically stimulated guinea pig left atria.
    Nature. 1980 Aug 21;286(5775):819-21 PMID: 7402355
  61. [Action potential and mechanogram of the heart muscle of homotherms as function of the beat frequency].
    Pflugers Arch Gesamte Physiol Menschen Tiere. 1954;260(1):24-39 PMID: 13236474
  62. Heart: excitation and contraction.
    Annu Rev Physiol. 1971;33:479-532 PMID: 4951054
  63. Three-micro-electrode voltage clamp experiments in calf cardiac Purkinje fibres: is slow inward current adequately measured?
    J Physiol. 1979 May;290(2):201-25 PMID: 469751
  64. Restoration by histamine of the calcium-dependent electrical and mechanical response in the guinea-pig papillary muscle partially depolarized by potassium.
    Naunyn Schmiedebergs Arch Pharmacol. 1976 Sep;294(3):261-9 PMID: 12480
  65. Effect of tetrodotoxin on action potentials of the conducting system in the dog heart.
    Am J Physiol. 1979 Apr;236(4):H561-7 PMID: 434221
  66. Relationship between internal calcium and outward current in mammalian ventricular muscle; a mechanism for the control of the action potential duration?
    J Physiol. 1976 Oct;262(1):15-37 PMID: 994035
  67. The steady state TTX-sensitive ("window") sodium current in cardiac Purkinje fibres.
    Pflugers Arch. 1979 Mar 16;379(2):137-42 PMID: 571107
  68. Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors.
    Pflugers Arch. 1972;335(4):309-22 PMID: 4673213
  69. Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude.
    Pflugers Arch. 1982 Oct;395(1):30-41 PMID: 6294586
Article Info
Journal
Pflugers Archiv : European journal of physiology
Abbr.
Pflugers Arch
ISSN
0031-6768
DOI
10.1007/BF00584964
Published
1982-10-00
Pages
19-29
Language
English
Region
Germany
NLM ID
0154720
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00584964 View journal details
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