Identification of a protein component of the Ca2+-dependent K+ channel by affinity labelling with apamin.

Animals Apamin/pharmacology Bee Venoms/pharmacology Brain/metabolism Calcium/metabolism Cross-Linking Reagents/pharmacology Hydrogen-Ion Concentration Ion Channels/drug effects,metabolism Kinetics Molecular Weight Nerve Tissue Proteins/isolation & purification,metabolism Potassium/metabolism Rats Succinimides/pharmacology Synaptic Membranes/metabolism

Bee Venoms Cross-Linking Reagents Ion Channels Nerve Tissue Proteins Succinimides Apamin disuccinimidyl beta-hydromuconate Potassium Calcium