Sodium inhibits both adenylate cyclase and high-affinity 3H-labeled p-aminoclonidine binding to alpha 2-adrenergic receptors in purified human platelet membranes.

Adenylyl Cyclase Inhibitors Binding, Competitive Blood Platelets/drug effects,metabolism Cell Membrane/metabolism Clonidine/analogs & derivatives,blood Epinephrine/pharmacology Humans In Vitro Techniques Kinetics Protein Binding Receptors, Adrenergic/metabolism Receptors, Adrenergic, alpha/metabolism Sodium/pharmacology

Adenylyl Cyclase Inhibitors Receptors, Adrenergic Receptors, Adrenergic, alpha apraclonidine Sodium Clonidine Epinephrine