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PMID: 6275116 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Host Susceptibility to endogenous viruses: defective, glycoprotein-expressing proviruses interfere with infections.

Journal of virology ·Vol. 40 ·No. 3 ·1981-12-00 ·Pages 745-51

Robinson HL, Astrin SM, Senior AM, Salazar FH

Abstract

Three defective endogenous avian leukosis viruses, ev3, ev6 and ev9, interfered with subgroup E virus infections, ev3, ev6, and ev9 expressed high levels of subgroup E envelope glycoproteins. These glycoproteins reduced the activity of cellular receptors for subgroup E viruses. ev3 and ev6 protected chickens and cultured cells from subgroup E virus infections.

MeSH Terms
Animals Avian Leukosis Virus/growth & development,physiology Cells, Cultured Chick Embryo Chickens/microbiology Defective Viruses/physiology Glycoproteins/physiology Receptors, Virus/metabolism Recombination, Genetic Viral Envelope Proteins Viral Interference Viral Proteins/physiology
Chemicals
Glycoproteins Receptors, Virus Viral Envelope Proteins Viral Proteins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Robinson H L
Astrin S M
Senior A M
Salazar F H
References (39)
39 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1981-12-00
Pages
745-51
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC256686
Subset
IM
Grants
NCI NIH HHS · CA 06927 · United States
NCI NIH HHS · CA 10467 · United States
NCI NIH HHS · CA 23086 · United States
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