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PMID: 6273720 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Biochemical functioning of mitochondria in normal and denervated mammalian skeletal muscle.

Muscle & nerve ·Vol. 4 ·No. 6 ·1981-00-00 ·Pages 514-9

Joffe M, Savage N, Isaacs H

Abstract

Mitochondrial preparations derived from denervated rat skeletal muscle and paired control muscle are characterized with respect to their oxidative and phosphorylative capacities. Our data indicate that there is an impairment within the first 2 energy coupling regions of the respiratory chain and within the ATPase complex itself.

MeSH Terms

Acid Phosphatase/metabolism Adenosine Triphosphatases/metabolism Animals Catalase/metabolism Electron Transport Complex IV/metabolism Female Kinetics Mitochondria, Muscle/metabolism Multienzyme Complexes/metabolism Muscle Denervation NADH, NADPH Oxidoreductases/metabolism Oxidative Phosphorylation Oxygen Consumption Rats Rats, Inbred Strains

Chemicals

Multienzyme Complexes Catalase NADH oxidase NADH, NADPH Oxidoreductases Electron Transport Complex IV Acid Phosphatase Adenosine Triphosphatases

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Joffe M

Savage N

Isaacs H

Article Info

Journal

Muscle & nerve

Abbr.

Muscle Nerve

ISSN

0148-639X

DOI

10.1002/mus.880040608

Published

1981-00-00

Pages

514-9

Language

English

Region

United States

NLM ID

7803146

Subset

External Links

PubMed source DOI: 10.1002/mus.880040608 View journal details

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Biochemical functioning of mitochondria in normal and denervated mammalian skeletal muscle.

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