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PMID: 6271566 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Increased urinary excretion of cyclic nucleotides in X-linked hypophosphatemic (Hyp) mice.

Experientia ·Vol. 37 ·No. 9 ·1981-00-00 ·Pages 978-9

Kiebzak GM, Meyer RA, Mish PM

Abstract

Hyp mice, a model for human X-linked hypophosphatemia, had elevated urinary cyclic AMP, cyclic GMP, and magnesium excretion compared to normal mice. The data suggest a renal origin of the urinary cyclic nucleotides. No significant differences in plasma cyclic AMP and cyclic GMP were observed between genotypes.

MeSH Terms
Animals Cyclic AMP/urine Cyclic GMP/urine Disease Models, Animal Female Hypophosphatemia, Familial/urine Magnesium/urine Male Mice Mice, Inbred C57BL/genetics Sex Factors X Chromosome
Chemicals
Cyclic AMP Cyclic GMP Magnesium
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Kiebzak G M
Meyer R A
Mish P M
References (13)
13 references, click to expand
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Article Info
Journal
Experientia
Abbr.
Experientia
ISSN
0014-4754
DOI
10.1007/BF01971790
Published
1981-00-00
Pages
978-9
Language
English
Region
Switzerland
NLM ID
0376547
Subset
IM
Grants
NCRR NIH HHS · RR-09016 · United States
External Links
PubMed source DOI: 10.1007/BF01971790
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