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PMID: 6270001 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Factors affecting the rate as which a trachoma strain of Chlamydia trachomatis establishes persistent infections in mouse fibroblasts (McCoy cells).

Infection and immunity ·Vol. 33 ·No. 3 ·1981-09-00 ·Pages 954-7

Lee CK

Abstract

Chlamydiae from mouse fibroblasts (McCoy cells) persistently infected with a trachoma strain (G17) of Chlamydia trachomatis repeatedly established new persistent infections in wild McCoy cells more rapidly than did wild chlamydiae. The density and nutritional state of the host cell populations may also influence the rate of establishment of persistent infections.

MeSH Terms

Animals Cell Line Chlamydia trachomatis/growth & development Cycloheximide/pharmacology Fibroblasts/microbiology Inclusion Bodies/ultrastructure Mice Time Factors

Chemicals

Cycloheximide

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Lee C K

References (6)

6 references, click to expand

Separation of protein synthesis in meningopneumonitisgent from that in L cells by differential susceptibility to cycloheximide.
J Bacteriol. 1968 Feb;95(2):327-32 PMID: 5640375
Competition between Chlamydia psittaci and L cells for host isoleucine pools: a limiting factor in chlamydial multiplication.
Infect Immun. 1975 Jul;12(1):211-20 PMID: 1095493
Cultivation of Chlamydia trachomatis in cycloheximide-treated mccoy cells.
J Clin Microbiol. 1977 Oct;6(4):328-31 PMID: 562356
Interaction between a trachoma strain of Chlamydia trachomatis and mouse fibroblasts (McCoy cells) in the absence of centrifugation.
Infect Immun. 1981 Feb;31(2):584-91 PMID: 7216462
Persistent infection of mouse fibroblasts (McCoy cells) with a trachoma strain of Chlamydia trachomatis.
Infect Immun. 1981 May;32(2):822-9 PMID: 7251149
ISOLATION OF THE TRACHOMA AGENT IN CELL CULTURE.
Proc Soc Exp Biol Med. 1965 Feb;118:354-9 PMID: 14268619

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.33.3.954-957.1981

Published

1981-09-00

Pages

954-7

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC350804

Subset

Grants

NIAID NIH HHS · AI-13175 · United States

NIGMS NIH HHS · GM-07183 · United States

External Links

PubMed source DOI: 10.1128/iai.33.3.954-957.1981 PMC Full Text View journal details

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Factors affecting the rate as which a trachoma strain of Chlamydia trachomatis establishes persistent infections in mouse fibroblasts (McCoy cells).

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