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PMID: 6268266 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Induced latency in pseudorabies vaccinated pigs.

Canadian journal of comparative medicine : Revue canadienne de medecine comparee ·Vol. 45 ·No. 1 ·1981-01-00 ·Pages 56-9

Mock RE, Crandell RA, Mesfin GM

Abstract

A latent pseudorabies virus infection was established in pigs despite vaccination with a modified-live pseudorabies virus vaccine. Although the vaccinated pigs developed high concentrations of antibody, virus was recovered from the tonsils and lungs of pigs treated with dexamethasone three months after inoculation with virulent virus. These results may explain why vaccination programs have failed to eliminate the persistence and spread of virulent pseudorabies virus in infected herds.

MeSH Terms
Animals Dexamethasone/pharmacology Female Herpesvirus 1, Suid/isolation & purification Male Palatine Tonsil/microbiology Pseudorabies/etiology,immunology,microbiology Swine/immunology Swine Diseases/etiology,immunology,microbiology Vaccination/veterinary
Chemicals
Dexamethasone
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Mock R E
Crandell R A
Mesfin G M
References (5)
5 references, click to expand
  1. Latent pseudorabies virus infection in pigs.
    Acta Virol. 1976 Jun;20(3):208-14 PMID: 9801
  2. Use of pseudorabies hyperimmune serum in naturally occurring pseudorabies in Illinois swine herds.
    J Am Vet Med Assoc. 1977 Jul 1;171(1):59-63 PMID: 560362
  3. Interaction of a combined feline viral rhinotracheitis-feline calicivirus vaccine and the FVR carrier state.
    Vet Rec. 1978 Sep 2;103(10):200-2 PMID: 212859
  4. Persistence of virulent pseudorabies virus in herds of vaccinated and nonvaccinated pigs.
    Acta Virol. 1971 Jan;15(1):87-94 PMID: 4395773
  5. Studies on immunisation of pigs with the Bartha strain of Aujeszky's disease virus.
    Res Vet Sci. 1975 Jul;19(1):17-22 PMID: 168626
Article Info
Journal
Canadian journal of comparative medicine : Revue canadienne de medecine comparee
Abbr.
Can J Comp Med
ISSN
0008-4050
Published
1981-01-00
Pages
56-9
Language
English
Region
Canada
NLM ID
0151747
PMCID
PMC1320121
Subset
IM
External Links
PubMed source PMC Full Text
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