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PMID: 6254506 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Identification of the C(6)-S-conjugate of leukotriene A with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A). Importance of the 11-cis-geometry for biological activity.

Biochemical and biophysical research communications ·Vol. 96 ·No. 1 ·1980-09-16 ·Pages 271-7

Lewis RA, Drazen JM, Austen KF, Clark DA, Corey EJ

Abstract

暂无摘要

MeSH Terms

Animals Arachidonic Acids/analysis,pharmacology Biological Assay Dose-Response Relationship, Drug Guinea Pigs Ileum/drug effects Leukotriene E4 Lung/drug effects,physiology Muscle Contraction/drug effects SRS-A/analysis Stereoisomerism Structure-Activity Relationship

Chemicals

Arachidonic Acids SRS-A Leukotriene E4

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Lewis R A

Drazen J M

Austen K F

Clark D A

Corey E J

Article Info

Journal

Biochemical and biophysical research communications

Abbr.

Biochem Biophys Res Commun

ISSN

0006-291X

DOI

10.1016/0006-291x(80)91210-3

Published

1980-09-16

Pages

271-7

Language

English

Region

United States

NLM ID

0372516

Subset

Grants

NIAID NIH HHS · AI-07722 · United States

NIAID NIH HHS · AI-10356 · United States

NHLBI NIH HHS · HL-17382 · United States

External Links

PubMed source DOI: 10.1016/0006-291x(80)91210-3 View journal details

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Identification of the C(6)-S-conjugate of leukotriene A with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A). Importance of the 11-cis-geometry for biological activity.

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