Slow GDP dissociation from the guanyl nucleotide site of turkey erythrocyte membranes is not the rate limiting step in the activation of adenylate cylase by beta-adrenergic receptors.

Adenylyl Cyclases/blood Animals Erythrocyte Membrane/drug effects,metabolism Erythrocytes/metabolism Guanine Nucleotides/blood Guanosine Diphosphate/blood Guanylyl Imidodiphosphate/pharmacology Isoproterenol/pharmacology Kinetics Receptors, Adrenergic/metabolism Receptors, Adrenergic, beta/metabolism Turkeys

Guanine Nucleotides Receptors, Adrenergic Receptors, Adrenergic, beta Guanosine Diphosphate Guanylyl Imidodiphosphate Adenylyl Cyclases Isoproterenol