The increase in bilayer fluidity of rat liver plasma membranes achieved by the local anesthetic benzyl alcohol affects the activity of intrinsic membrane enzymes.

3',5'-Cyclic-AMP Phosphodiesterases/metabolism Adenosine Triphosphatases/metabolism Adenylyl Cyclases/metabolism Alkaline Phosphatase/metabolism Animals Benzyl Alcohols/pharmacology Benzyl Compounds/pharmacology Cell Membrane/drug effects,enzymology,metabolism Electron Spin Resonance Spectroscopy Glucagon/pharmacology Liver/enzymology,metabolism Male Membrane Fluidity/drug effects Nucleotidases/metabolism Rats

Benzyl Alcohols Benzyl Compounds Glucagon Nucleotidases Alkaline Phosphatase 3',5'-Cyclic-AMP Phosphodiesterases Adenosine Triphosphatases Adenylyl Cyclases