The neurite-promoting effect of fibroblast growth factor on PC12 cells.

Biochemical and biophysical research communications ·Vol. 114 ·No. 3 ·1983-08-12 ·Pages 1189-93

Togari A, Baker D, Dickens G, Guroff G

Abstract

Treatment of PC12 cells with fibroblast growth factor(s) from either brain or pituitary caused neurite outgrowth comparable to that produced by nerve growth factor. The neurite outgrowth was preceded by a substantial rise in the activity of ornithine decarboxylase.

MeSH Terms

Animals Cell Differentiation/drug effects Cells, Cultured Fibroblast Growth Factors Growth Substances/pharmacology Nerve Growth Factors/pharmacology Neurons/cytology Ornithine Decarboxylase/biosynthesis Peptides/pharmacology Pheochromocytoma/pathology Rats

Chemicals

Growth Substances Nerve Growth Factors Peptides Fibroblast Growth Factors Ornithine Decarboxylase

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Togari A

Baker D

Dickens G

Guroff G

Article Info

Journal

Biochemical and biophysical research communications

Abbr.

Biochem Biophys Res Commun

ISSN

0006-291X

DOI

10.1016/0006-291x(83)90688-5

Published

1983-08-12

Pages

1189-93

Language

English

Region

United States

NLM ID

0372516

Subset

External Links

PubMed source DOI: 10.1016/0006-291x(83)90688-5 View journal details

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The neurite-promoting effect of fibroblast growth factor on PC12 cells.

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