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PMID: 6218094 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Six widespread bacterial clones among Escherichia coli K1 isolates.

Infection and immunity ·Vol. 39 ·No. 1 ·1983-01-00 ·Pages 315-35

Achtman M, Mercer A, Kusecek B, Pohl A, Heuzenroeder M, Aaronson W, Sutton A, Silver RP

Abstract

Variable properties among Escherichia coli isolates include serotype, electrophoretic migration of major outer membrane proteins, metabolic properties, production of hemolysin or colicin or both, and plasmid content. These characteristics were compared in E. coli strains of capsular types K1, K5, K92, and K100 and in non-encapsulated isolates. The 234 bacterial strains from the United States and Europe which we studied had been isolated from healthy or diseased individuals recently or as long ago as 1941. Regardless of source, most O7:K1, O16:K1, and O75:K100 isolates could be assigned to three unique, serotype-specific groups, which were interpreted as representing three bacterial clones. Two bacterial (sub)clones each were discerned among the O18:K1 and O18:K5 isolates, and two further, distinct clones were discerned among the O1:K1 isolates. The implications of these results for epidemiological analyses and for virulence are discussed.

MeSH Terms
Cell Membrane/analysis Escherichia coli/classification,genetics,growth & development Flagella Niacinamide/pharmacology Plasmids Serotyping
Chemicals
Niacinamide
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Achtman M
Mercer A
Kusecek B
Pohl A
Heuzenroeder M
Aaronson W
Sutton A
Silver R P
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.39.1.315-335.1983
Published
1983-01-00
Pages
315-35
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC347943
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.39.1.315-335.1983 PMC Full Text View journal details
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