Permeability increase in black lipid membrane induced by compound 48/80.

Biochimica et biophysica acta ·Vol. 805 ·No. 1 ·1984-09-14 ·Pages 127-30

Shibata H, Mio M, Tasaka K

Abstract

When compound 48/80, a potent histamine liberator, was added in the aqueous phase facing the black lipid membrane, the conductivity of the membrane was remarkably increased. Although valinomycin displayed a distinct selectivity for K+ movement, such selection for ionic permeability was not observed in the case of compound 48/80.

MeSH Terms

Animals Cholesterol Electric Conductivity Histamine Release/drug effects Liposomes Male Mast Cells/drug effects,immunology Models, Biological Permeability Phosphatidylcholines Rats Rats, Inbred Strains Valinomycin p-Methoxy-N-methylphenethylamine/pharmacology

Chemicals

Liposomes Phosphatidylcholines Valinomycin p-Methoxy-N-methylphenethylamine Cholesterol

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Shibata H

Mio M

Tasaka K

Article Info

Journal

Biochimica et biophysica acta

Abbr.

Biochim Biophys Acta

ISSN

0006-3002

DOI

10.1016/0167-4889(84)90045-4

Published

1984-09-14

Pages

127-30

Language

English

Region

Netherlands

NLM ID

0217513

Subset

External Links

PubMed source DOI: 10.1016/0167-4889(84)90045-4

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Permeability increase in black lipid membrane induced by compound 48/80.

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