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PMID: 6201200 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

5-A Fourier map of gramicidin A phased by deuterium-hydrogen solvent difference neutron diffraction.

Biophysical journal ·Vol. 45 ·No. 3 ·1984-03-00 ·Pages 503-7

Koeppe RE, Schoenborn BP

Abstract

Crystals of ion-free gramicidin A (P212121: a = 24.61, b = 32.28, c = 32.52) have been investigated using neutron diffraction. A difference analysis of crystals soaked in ethanol/H2O as opposed to ethanol-d6/D2O has led to single isomorphous replacement Fourier projections of the structure at 5-A resolution. The gramicidin dimer appears to be a 32-A-long cylinder oriented parallel to the c-axis in these crystals.

MeSH Terms
Crystallography/methods Deuterium Fourier Analysis Gramicidin Hydrogen Models, Molecular Neutrons Solvents
Chemicals
Solvents Gramicidin Hydrogen Deuterium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Koeppe R E
Schoenborn B P
References (12)
12 references, click to expand
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Article Info
Journal
Biophysical journal
Abbr.
Biophys J
ISSN
0006-3495
DOI
10.1016/S0006-3495(84)84186-7
Published
1984-03-00
Pages
503-7
Language
English
Region
United States
NLM ID
0370626
PMCID
PMC1434879
Subset
IM
Grants
NIGMS NIH HHS · GM-24032 · United States
NINDS NIH HHS · NIH-NS-16449 · United States
NINDS NIH HHS · NS-00648 · United States
External Links
PubMed source DOI: 10.1016/S0006-3495(84)84186-7 PMC Full Text View journal details
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