Home LiteratureArticle Details
PMID: 6187006 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Isolation of pancreatic trypsin inhibitor from bovine pituitary glands.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 80 ·No. 5 ·1983-03-00 ·Pages 1204-6

Li CH, Chung D

Abstract

A trypsin inhibitor has been isolated from bovine pituitary extracts. From its amino acid composition, NH2-terminal residue, mobility in paper electrophoresis, and behavior in high-performance liquid chromatography and from the tryptic pattern of the performic acid-oxidized material, it appears that the inhibitor is identical to the Kunitz and Northrop pancreatic trypsin inhibitor.

MeSH Terms
Amino Acids/analysis Animals Aprotinin/isolation & purification Cattle Chromatography, Gel Chromatography, High Pressure Liquid Chromatography, Ion Exchange Pituitary Gland/analysis
Chemicals
Amino Acids Aprotinin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Li C H
Chung D
References (12)
12 references, click to expand
  1. Cell-free translation product containing corticotropin and beta-endorphin encoded by messenger RNA from anterior lobe and intermediate lobe of bovine pituitary.
    FEBS Lett. 1977 Dec 1;84(1):105-9 PMID: 73478
  2. Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor.
    Nature. 1979 Mar 29;278(5703):423-7 PMID: 221818
  3. Adrenocorticotropins. 44. Total synthesis of the human hormone by the solid-phase method.
    J Am Chem Soc. 1973 Feb 21;95(4):1310-5 PMID: 4347148
  4. Hydrolysis of proteins with p-toluenesulfonic acid. Determination of tryptophan.
    J Biol Chem. 1971 May 10;246(9):2842-8 PMID: 5102928
  5. Common precursor to corticotropins and endorphins.
    Proc Natl Acad Sci U S A. 1977 Jul;74(7):3014-8 PMID: 197529
  6. Studies on pituitary lactogenic hormone. XVII. Oxidation of the ovine hormone with performic acid.
    J Biol Chem. 1957 Nov;229(1):157-63 PMID: 13491569
  7. Pituitary proteinase I: Purification and action on growth hormone and prolactin.
    J Biol Chem. 1960 Jun;235:1694-9 PMID: 13820054
  8. Isolation and characterization of delta-melanotropin, a new peptide from bovine pituitary glands.
    Biochem Biophys Res Commun. 1982 Sep 16;108(1):118-23 PMID: 7150276
  9. THE BASIC TRYPSIN INHIBITOR OF BOVINE PANCREAS. IV. THE LINEAR SEQUENCE OF THE 58 AMINO ACIDS.
    Biochem Biophys Res Commun. 1965 Jan 18;18:255-8 PMID: 14282026
  10. Synthesis and analgesic activity of human beta-endorphin.
    J Med Chem. 1977 Mar;20(3):325-8 PMID: 845862
  11. Characterization of a common precursor to corticotropin and beta-lipotropin: cell-free synthesis of the precursor and identification of corticotropin peptides in the molecule.
    Proc Natl Acad Sci U S A. 1977 Nov;74(11):4826-30 PMID: 200934
  12. Proteolytic activity of pituitary extracts.
    J Biol Chem. 1951 Aug;191(2):651-64 PMID: 14861211
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.80.5.1204
Published
1983-03-00
Pages
1204-6
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC393562
Subset
IM
Grants
NIGMS NIH HHS · GM-2907 · United States
NIMH NIH HHS · MH-30245 · United States
External Links
PubMed source DOI: 10.1073/pnas.80.5.1204 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2