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PMID: 6183453 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Caprine arthritis-encephalitis virus is distinct from visna and progressive pneumonia viruses as measured by genome sequence homology.

Journal of virology ·Vol. 44 ·No. 2 ·1982-11-00 ·Pages 755-8

Roberson SM, McGuire TC, Klevjer-Anderson P, Gorham JR, Cheevers WP

Abstract

Competitive inhibition of hybridization between (125)I-labeled caprine arthritis-encephalitis viral RNA and homologous cDNA by heterologous viral RNA shows that the caprine retrovirus shares <20% genome sequence homology with visna and progressive pneumonia viruses. These viruses, however, are indistinguishable in immunodiffusion reactions involving the major structural protein (p28).

MeSH Terms
Animals Antigens, Viral/immunology Base Sequence DNA Epitopes Genes, Viral Goats Nucleic Acid Hybridization RNA, Viral Retroviridae/genetics,immunology Species Specificity Viral Proteins/immunology Visna-maedi virus/genetics,immunology
Chemicals
Antigens, Viral Epitopes RNA, Viral Viral Proteins DNA
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Roberson S M
McGuire T C
Klevjer-Anderson P
Gorham J R
Cheevers W P
References (17)
17 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1982-11-00
Pages
755-8
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC256326
Subset
IM
Grants
NIADDK NIH HHS · AM 27680 · United States
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