An 'on grid' electron microscopic method for studying the interaction and fusion of influenza A virus with human erythrocyte membranes.

Journal of virological methods ·Vol. 3 ·No. 5 ·1981-12-00 ·Pages 271-6

Fidgen KJ, Tisdale M

Abstract

An 'on grid' negative staining method was developed to study the interaction of influenza virus with erythrocyte membranes. The virus was reacted in situ with cells which had been immobilised on an electron microscope grid. Fusion between influenza virus and the membrane of erythrocyte ghosts was clearly seen using this method.

MeSH Terms

Erythrocyte Membrane/physiology,ultrastructure Erythrocytes/ultrastructure Humans Influenza A virus/physiology,ultrastructure Microscopy, Electron/methods Staining and Labeling

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fidgen K J

Tisdale M

Article Info

Journal

Journal of virological methods

Abbr.

J Virol Methods

ISSN

0166-0934

DOI

10.1016/0166-0934(81)90064-1

Published

1981-12-00

Pages

271-6

Language

English

Region

Netherlands

NLM ID

8005839

Subset

External Links

PubMed source DOI: 10.1016/0166-0934(81)90064-1 View journal details

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An 'on grid' electron microscopic method for studying the interaction and fusion of influenza A virus with human erythrocyte membranes.

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