Further studies on antigen variation in Staphylococcus aureus.

Journal of clinical microbiology ·Vol. 13 ·No. 2 ·1981-02-00 ·Pages 245-7

Pereira AT

Abstract

The plating of successive Staphylococcus aureus subcultures of daily transfers proved that discontinuous variation resembling a genetic mutation and selective outgrowth of the variant are responsible for antigen variation. Every subculture of S. aureus, when repeatedly transferred, contained a mixture of cells with original antigen 17 (or 13) and final antigen 1 (or 3) that are relevant for research, serological diagnosis, and epidemiological study of staphylococcal diseases.

MeSH Terms

Antigens, Bacterial Epitopes Genetic Variation Mutation Staphylococcus aureus/genetics,growth & development,immunology

Chemicals

Antigens, Bacterial Epitopes

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Pereira A T

References (10)

10 references, click to expand

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Ann N Y Acad Sci. 1974 Jul 31;236(0):485-94 PMID: 4529278
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Br J Exp Pathol. 1958 Apr;39(2):199-202 PMID: 13523075
Antigenic loss variation in Staphylococcus aureus.
J Pathol Bacteriol. 1961 Jan;81:151-6 PMID: 13734244
STAPHYLOCOCCAL INFECTION IN THE MOUSE. II. VARIATION IN INTRACEREBRAL VIRULENCE OF A SINGLE STRAIN OF STAPHYLOCOCCUS.
Br J Exp Pathol. 1963 Oct;44:497-501 PMID: 14066124
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Article Info

Journal

Journal of clinical microbiology

Abbr.

J Clin Microbiol

ISSN

0095-1137

DOI

10.1128/jcm.13.2.245-247.1981

Published

1981-02-00

Pages

245-7

Language

English

Region

United States

NLM ID

7505564

PMCID

PMC273770

Subset

External Links

PubMed source DOI: 10.1128/jcm.13.2.245-247.1981 PMC Full Text View journal details

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Further studies on antigen variation in Staphylococcus aureus.

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