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PMID: 6162075 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Variations in phenotype of relB mutants of Escherichia coli and the effect of pus and sup mutations.

Molecular & general genetics : MGG ·Vol. 180 ·No. 2 ·1980-00-00 ·Pages 429-37

Diderichsen B, Desmarez L

Abstract

Three independent relB mutants were studied. During amino acid starvation they all accumulate RNA and produce an inhibitor of in vitro protein synthesis; after starvation growth is retarded for hours. The mutants differ in the degree to which the common phenotype is expressed, but the characteristic thermolability of the inhibitor is the same. The phenotype of the relB mutants is accentuated by amber suppressors, and this effect is counteracted by a mutation, pus-1 that maps at 19.5 min near aroA.

MeSH Terms
Amino Acids/deficiency Bacterial Proteins/biosynthesis Escherichia coli/genetics,growth & development Mutation Phenotype Protein Biosynthesis RNA, Bacterial/metabolism RNA, Messenger/metabolism Suppression, Genetic Temperature
Chemicals
Amino Acids Bacterial Proteins RNA, Bacterial RNA, Messenger
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Diderichsen B
Desmarez L
References (12)
12 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00425859
Published
1980-00-00
Pages
429-37
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00425859
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