A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data.

Adenylyl Cyclases/metabolism Adrenergic beta-Agonists/metabolism Animals Anura Binding Sites Binding, Competitive Computers Dihydroalprenolol/metabolism Dose-Response Relationship, Drug Erythrocyte Membrane/metabolism In Vitro Techniques Ligands/metabolism Methods Models, Theoretical Nucleotides/pharmacology Receptors, Adrenergic/analysis Receptors, Adrenergic, beta/analysis,metabolism

Adrenergic beta-Agonists Ligands Nucleotides Receptors, Adrenergic Receptors, Adrenergic, beta Dihydroalprenolol Adenylyl Cyclases