Resistance of the antibiotic target site.

Anti-Bacterial Agents/pharmacology Bacteria/drug effects,genetics,metabolism Bacterial Proteins Binding Sites Carrier Proteins/metabolism DNA Replication/drug effects DNA, Bacterial/biosynthesis DNA-Directed RNA Polymerases/metabolism Drug Resistance, Microbial Hexosyltransferases Lactams Muramoylpentapeptide Carboxypeptidase/metabolism Penicillin-Binding Proteins Peptidyl Transferases Protein Biosynthesis/drug effects RNA, Ribosomal/biosynthesis Ribosomal Proteins/biosynthesis Ribosomes/metabolism Topoisomerase II Inhibitors Transcription, Genetic/drug effects

Anti-Bacterial Agents Bacterial Proteins Carrier Proteins DNA, Bacterial Lactams Penicillin-Binding Proteins RNA, Ribosomal Ribosomal Proteins Topoisomerase II Inhibitors Peptidyl Transferases Hexosyltransferases DNA-Directed RNA Polymerases Muramoylpentapeptide Carboxypeptidase