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PMID: 6094296 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Detection of pX proteins in human T-cell leukemia virus (HTLV)-infected cells by using antibody against peptide deduced from sequences of X-IV DNA of HTLV-I and Xc DNA of HTLV-II proviruses.

Gan ·Vol. 75 ·No. 9 ·1984-09-00 ·Pages 752-5

Miwa M, Shimotohno K, Hoshino H, Fujino M, Sugimura T

Abstract

A 41-kilodalton protein was detected in four human T-cell leukemia virus type I (HTLV-I)-infected cell lines, a 68-kilodalton glycoprotein in MT-2 cells, and a 38-kilodalton protein in an HTLV-II-infected cell line by using antibody against a synthetic dodecapeptide, a portion of the polypeptide deduced from the nucleotide sequence of the X regions of HTLVs.

MeSH Terms

Animals Antibodies, Viral/immunology Base Sequence Cell Line DNA, Viral Deltaretrovirus/genetics Humans Immunization Leukemia/metabolism Molecular Weight Peptides/immunology Rabbits Retroviridae Infections/metabolism Trans-Activators Viral Proteins/analysis

Chemicals

Antibodies, Viral DNA, Viral Peptides Trans-Activators Viral Proteins

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Miwa M

Shimotohno K

Hoshino H

Fujino M

Sugimura T

Article Info

Journal

Gan

Abbr.

Gan

ISSN

0016-450X

Published

1984-09-00

Pages

752-5

Language

English

Region

Japan

NLM ID

0151745

Subset

External Links

PubMed source

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Detection of pX proteins in human T-cell leukemia virus (HTLV)-infected cells by using antibody against peptide deduced from sequences of X-IV DNA of HTLV-I and Xc DNA of HTLV-II proviruses.

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