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PMID: 6090390 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Vibrio cholerae enterotoxin genes: nucleotide sequence analysis of DNA encoding ADP-ribosyltransferase.

Journal of bacteriology ·Vol. 159 ·No. 3 ·1984-09-00 ·Pages 1086-9

Lockman HA, Galen JE, Kaper JB

Abstract

The nucleotide sequence of the DNA encoding the ADP-ribosyltransferase (A1) fragment of cholera enterotoxin was determined. A putative precursor of the A1 peptide contains an 18-amino acid leader peptide, and the mature A1 peptide contains 194 amino acids. The primary structure of the A1 fragment from cholera enterotoxin is more related to that from a human enterotoxigenic Escherichia coli than to that from a porcine enterotoxigenic E. coli.

MeSH Terms
Amino Acid Sequence Base Sequence DNA Restriction Enzymes Enterotoxins/genetics Genes Genes, Bacterial Nucleotidyltransferases/genetics Poly(ADP-ribose) Polymerases Vibrio cholerae/enzymology,genetics
Chemicals
Enterotoxins Poly(ADP-ribose) Polymerases Nucleotidyltransferases DNA Restriction Enzymes
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Lockman H A
Galen J E
Kaper J B
References (21)
21 references, click to expand
  1. The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.
    Proc Natl Acad Sci U S A. 1974 Apr;71(4):1342-6 PMID: 4598299
  2. The arrangement of subunits in cholera toxin.
    Biochemistry. 1976 Mar 23;15(6):1242-8 PMID: 3214
  3. Neutralization of Salmonella toxin-induced elongation of Chinese hamster ovary cells by cholera antitoxin.
    Infect Immun. 1977 Mar;15(3):988-92 PMID: 67084
  4. DNA sequencing with chain-terminating inhibitors.
    Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 PMID: 271968
  5. ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.
    Proc Natl Acad Sci U S A. 1978 Jul;75(7):3050-4 PMID: 210449
  6. Origin of the enzymatically active A1 fragment of cholera toxin.
    J Infect Dis. 1979 Jun;139(6):674-80 PMID: 448194
  7. Regulatory sequences involved in the promotion and termination of RNA transcription.
    Annu Rev Genet. 1979;13:319-53 PMID: 94251
  8. Adenosine diphosphate-ribosylation of adenylate cyclase catalyzed by heat-labile enterotoxin of Escherichia coli: comparison with cholera toxin.
    J Infect Dis. 1980 Jan;141(1):64-70 PMID: 6988518
  9. Isolation and characterization of a precursor form of the 'A' subunit of cholera toxin.
    FEBS Lett. 1981 Apr 20;126(2):187-90 PMID: 7238869
  10. Subunit number and arrangement in Escherichia coli heat-labile enterotoxin.
    Infect Immun. 1981 Sep;33(3):677-82 PMID: 7026442
  11. Escherichia coli heat-labile enterotoxin. Nucleotide sequence of the A subunit gene.
    J Biol Chem. 1982 May 25;257(10):5716-21 PMID: 6279611
  12. A set of synthetic oligodeoxyribonucleotide primers for DNA sequencing in the plasmid vector pBR322.
    Gene. 1981 Dec;16(1-3):21-6 PMID: 6282692
  13. Immunological cross-reactivity of enterotoxins of Aeromonas hydrophila and cholera toxin.
    Clin Exp Immunol. 1982 Jan;47(1):34-42 PMID: 7047024
  14. A simple method for displaying the hydropathic character of a protein.
    J Mol Biol. 1982 May 5;157(1):105-32 PMID: 7108955
  15. A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments.
    Gene. 1982 Oct;19(3):269-76 PMID: 6295880
  16. Monoclonal antibodies to cholera toxin with special reference to cross-reactions with Escherichia coli heat-labile enterotoxin.
    Infect Immun. 1983 May;40(2):570-6 PMID: 6840852
  17. Vibrio cholerae hemagglutinin/lectin/protease hydrolyzes fibronectin and ovomucin: F.M. Burnet revisited.
    Proc Natl Acad Sci U S A. 1983 Feb;80(4):1092-5 PMID: 6341990
  18. Cholera-like enterotoxin produced by Campylobacter jejuni. Characterisation and clinical significance.
    Lancet. 1983 Jul 30;2(8344):250-3 PMID: 6135079
  19. Nucleotide sequence analysis of the A2 and B subunits of Vibrio cholerae enterotoxin.
    J Biol Chem. 1983 Nov 25;258(22):13722-6 PMID: 6315707
  20. Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development.
    Nature. 1983 Dec 8-14;306(5943):551-7 PMID: 6646234
  21. Primary structure of heat-labile enterotoxin produced by Escherichia coli pathogenic for humans.
    J Biol Chem. 1984 Apr 25;259(8):5037-44 PMID: 6325417
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1984-09-00
Pages
1086-9
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC215778
Subset
IM
Grants
NIAID NIH HHS · N01AI12666 · United States
NIAID NIH HHS · R22AI19716 · United States
Databases
GENBANK
K02679
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