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PMID: 60707 Published · ppublish English Journal Article

gag Gene of mammalian type-C RNA tumour viruses.

Nature ·Vol. 262 ·No. 5569 ·1976-08-12 ·Pages 554-9

Barbacid M, Stephenson JR, Aaronson SA

Abstract

The translation product of the gag gene of mammalian type-c- RNA viruses is a 65,000-68,000 molecular weight precursor polypeptide (Pr65) whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10. An immunological approach has been used to establish the arrangement of the sequences coding for these proteins within the viral genome as (5') p15-p12-p30-p10 (3').

MeSH Terms
Chromosome Mapping Defective Viruses Epitopes Genes Helper Viruses Protein Precursors/biosynthesis Rauscher Virus Retroviridae Sarcoma Viruses, Murine Viral Proteins/biosynthesis,immunology
Chemicals
Epitopes Protein Precursors Viral Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Barbacid M
Stephenson J R
Aaronson S A
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
Published
1976-08-12
Pages
554-9
Language
English
Region
England
NLM ID
0410462
Subset
IM
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